SLC12A3 Antibody

Size

100ug

Clone Number

Aliases

FLJ96318 antibody; Na Cl cotransporter antibody; Na Cl symporter antibody; Na-Cl symporter antibody; NaCl electroneutral thiazide sensitive cotransporter antibody; NCC antibody; NCCT antibody; S12A3_HUMAN antibody; slc12a3 antibody; Solute carrier family 12 (sodium/chloride transporters) member 3 antibody; Solute carrier family 12 member 3 antibody; Thiazide sensitive Na Cl cotransporter antibody; Thiazide sensitive sodium chloride cotransporter antibody; Thiazide-sensitive sodium-chloride cotransporter antibody; TSC antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P55017

Immunogen

Recombinant Human Solute carrier family 12 member 3 protein (791-952AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IF; Recommended dilution: IF:1:50-1:200

Background

Electroneutral sodium and chloride ion cotransporter. In kidney distal convoluted tubules, key mediator of sodium and chloride reabsorption (PubMed:21613606, PubMed:22009145). Receptor for the proinflammatory cytokine IL18. Contributes to IL18-induced cytokine production, including IFNG, IL6, IL18 and CCL2. May act either independently of IL18R1, or in a complex with IL18R1 (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SLC12A3

Research Areas

Cardiovascular; Metabolism; Signal transduction