SLC11A1 Antibody, FITC conjugated

Size

100ug

Clone Number

Aliases

LSH antibody; Natural resistance associated macrophage protein 1 antibody; Natural resistance-associated macrophage protein 1 antibody; NRAM1_HUMAN antibody; NRAMP 1 antibody; NRAMP antibody; PBC antibody; SLC11A1 antibody; Solute carrier family 11 (proton coupled divalent metal ion transporters) member 1 antibody; solute carrier family 11 (sodium/phosphate symporters) member 1 antibody; Solute carrier family 11 member 1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P49279

Immunogen

Recombinant Human Natural resistance-associated macrophage protein 1 protein (1-58AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

Background

Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

FITC

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SLC11A1

Research Areas

Immunology; Metabolism; Signal transduction