SIAH1 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease| the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants| some encoding different isoforms and others that have not been fully characterized.

Reactivity

Human, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human SIAH1

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

31020

synonyms

SIAH1