ABCbiolab
SKU:ABCCS54041
SHOC2 Antibody, HRP conjugated
SHOC2 Antibody, HRP conjugated
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Size
100ug
Clone Number
Aliases
KIAA0862 antibody; Leucine-rich repeat protein SHOC-2 antibody; Protein soc-2 homolog antibody; Protein Sur-8 homolog antibody; Ras-binding protein Sur-8 antibody; SHOC2 antibody; SHOC2_HUMAN antibody
Immunogen Species
Homo sapiens (Human)
UniProt ID
Q9UQ13
Immunogen
Recombinant Human Leucine-rich repeat protein SHOC-2 protein (3-89AA)
Raised in
Rabbit
Species Reactivity
Human
Tested Applications
ELISA
Background
Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the \'Ser-259\' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Conjugate
HRP
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Stroage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names
SHOC2
Research Areas
Cell biology
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