SHOC2 Antibody

Size

100ug

Clone Number

Aliases

KIAA0862 antibody; Leucine-rich repeat protein SHOC-2 antibody; Protein soc-2 homolog antibody; Protein Sur-8 homolog antibody; Ras-binding protein Sur-8 antibody; SHOC2 antibody; SHOC2_HUMAN antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9UQ13

Immunogen

Recombinant Human Leucine-rich repeat protein SHOC-2 protein (3-89AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Background

Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the \\\'Ser-259\\\' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SHOC2

Research Areas

Cell biology