shha Antibody

Size

100ug

Clone Number

Aliases

shha antibody; shh antibody; vhh1 antibody; Sonic hedgehog protein A antibody; SHHA antibody; Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains antibody; ShhNC antibody; VHH-1) [Cleaved into: Sonic hedgehog protein A N-product antibody; Shh N-terminal processed signaling domains antibody; ShhNp antibody; Sonic hedgehog protein N-product antibody; ShhN)] antibody

Immunogen Species

Danio rerio (Zebrafish) (Brachydanio rerio)

UniProt ID

Q92008

Immunogen

Recombinant Zebrafish Sonic hedgehog protein A protein (24-197AA)

Raised in

Rabbit

Species Reactivity

Zebrafish

Tested Applications

ELISA

Background

Intercellular signal essential for a variety of patterning events during development. Signal produced by the notochord that induces somite patterning, dorso-ventral patterning of the brain and early patterning of the developing eyes. Displays floor plate-inducing activity. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

shha

Research Areas

Others