SH3RF1 Antibody

Size

100ug

Clone Number

Aliases

SH3RF1 antibody; KIAA1494 antibody; POSH antibody; POSH1 antibody; RNF142 antibody; SH3MD2 antibody; E3 ubiquitin-protein ligase SH3RF1 antibody; EC 2.3.2.27 antibody; Plenty of SH3s antibody; Protein POSH antibody; RING finger protein 142 antibody; RING-type E3 ubiquitin transferase SH3RF1 antibody; SH3 domain-containing RING finger protein 1 antibody; SH3 multiple domains protein 2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q7Z6J0

Immunogen

Recombinant Human E3 ubiquitin-protein ligase SH3RF1 protein (628-742AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IF; Recommended dilution: IF:1:200-1:500

Background

Acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9) (By similarity). May be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SH3RF1

Research Areas

Others