SH3G3 Polyclonal Antibody

Ab type

Primary antibody

Background

An N-terminal amphipathic helix, the BAR domain and a second amphipathic helix inserted into helix 1 of the BAR domain (N-BAR domain) induce membrane curvature and bind curved membranes.,Implicated in endocytosis. May recruit other proteins to membranes with high curvature.,Belongs to the endophilin family.,Contains 1 BAR domain.,Contains 1 SH3 domain.,subcellular location:Associated with postsynaptic endosomes in hippocampal neurons. Associated with presynaptic endosomes in olfactory neurons.,subunit:Interacts with ARC (By similarity). Interacts with DNM1, SGIP1 and SYNJ1. Interacts with the huntingtin exon 1 protein (HDEX1P) containing a glutamine repeat in the pathological range and promotes formation of insoluble polyglutamine-containing aggregates in vivo.,tissue specificity:Brain and testis.,

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from part region of human protein

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

Endophilin-A3 ;EEN-B2;Endophilin-3;SH3 domain protein 2C;SH3 domain-containing GRB2-like protein 3