SH3BP1 Antibody

Size

100ug

Clone Number

Aliases

3BP 1 antibody; 3BP-1 antibody; 3BP1_HUMAN antibody; ARHGAP43 antibody; dJ37E16 antibody; FLJ21318 antibody; OTTHUMP00000028981 antibody; SH3 domain binding protein 1 antibody; SH3 domain-binding protein 1 antibody; Sh3bp1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9Y3L3

Immunogen

Recombinant Human SH3 domain-binding protein 1 protein (161-266AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:200-1:500

Background

Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SH3BP1

Research Areas

Signal transduction