SGK1(Phospho Ser78) Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human SGK around the phosphorylation site of Ser78. AA range:41-90

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

48942

synonyms

Serine/threonine-protein kinase Sgk1; SGK1; SGK; Serine/threonine-protein kinase Sgk1; Serum/glucocorticoid-regulated kinase 1