SGCG Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes gamma-sarcoglycan| one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin| syntrophin| alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy| in particular limb-girdle muscular dystrophy| type 2C (LGMD2C).

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human SGCG

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

32010

synonyms

SGCG