SG196 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a protein that may be involved in the presentation of the laminin-binding O-linked carbohydrate chain of alpha-dystroglycan (a-DG)| which forms transmembrane linkages between the extracellular matrix and the exoskeleton. Some pathogens use this O-linked carbohydrate unit for host entry. Loss of function compound heterozygous mutations in this gene were found in a human patient affected by the Walker-Warburg syndrome (WWS) phenotype. Mice lacking this gene contain misplaced neurons (heterotopia) in some regions of the brain| possibly from defects in neuronal migration. Alternative splicing of this gene results in multiple transcript variants.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human SG196

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

38500

synonyms

SG196