SF3B1 Antibody, Biotin conjugated

Size

100ug

Clone Number

Aliases

Hsh155 antibody; OTTHUMP00000205700 antibody; OTTHUMP00000205702 antibody; OTTHUMP00000225001 antibody; OTTHUMP00000225002 antibody; Pre mRNA processing 10 antibody; Pre mRNA splicing factor SF3b, 155 kDa subunit antibody; Pre-mRNA splicing factor SF3b 155 kDa subunit antibody; Pre-mRNA-splicing factor SF3b 155 kDa subunit antibody; PRP10 antibody; PRPF10 antibody; SAP 155 antibody; SAP155 antibody; sf3b1 antibody; SF3B1_HUMAN antibody; SF3b155 antibody; Spliceosome associated protein 155 antibody; Spliceosome-associated protein 155 antibody; Splicing factor 3B subunit 1 antibody; Splicing factor 3b, subunit 1, 155kDa antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O75533

Immunogen

Recombinant Human Splicing factor 3B subunit 1 protein (186-378AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Subunit of the splicing factor SF3B required for \'A\' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the \'E\' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SF3B1

Research Areas

Epigenetics and Nuclear Signaling