SETMAR Polyclonal Antibody

Ab type

Primary antibody

Background

SETMAR (SET domain and mariner transposase fusion gene) encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. SETMAR exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human SETMAR. AA range:350-400

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

76669

synonyms

SETMAR; Histone-lysine N-methyltransferase SETMAR; SET domain and mariner transposase fusion gene-containing protein; HsMar1; Metnase