SESN3 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose| insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human SESN3

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

54120

synonyms

SESN3