SENP2 Antibody

Size

100ug

Clone Number

Aliases

Axam2 antibody; DKFZp762A2316 antibody; KIAA1331 antibody; Senp2 antibody; SENP2_HUMAN antibody; Sentrin specific protease 2 antibody; Sentrin-specific protease 2 antibody; Sentrin/SUMO specific protease SENP2 antibody; Sentrin/SUMO-specific protease SENP2 antibody; SMT3 specific isopeptidase 2 antibody; SMT3-specific isopeptidase 2 antibody; Smt3ip2 antibody; SUMO1/sentrin/SMT3 specific peptidase 2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9HC62

Immunogen

Recombinant Human Sentrin-specific protease 2 protein (138-324AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Background

Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Deconjugates SUMO2 from MTA1. Plays a dynamic role in adipogenesis by desumoylating and promoting the stabilization of CEBPB (PubMed:20194620).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SENP2

Research Areas

Epigenetics and Nuclear Signaling; Cell biology