SEMA4C Antibody

Size

100ul

Clone Number

Aliases

KIAA1739 antibody; M-SEMA-F antibody; S4c antibody; SEM4C_HUMAN antibody; Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C antibody; SEMA4C antibody; SEMACL1 antibody; SEMAF antibody; SEMAI antibody; Semaphorin-4C antibody; UNQ5855/PRO34487 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9C0C4

Immunogen

Recombinant Human Semaphorin-4C protein (749-833AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at \\\'Tyr-1248\\\'. Required for normal brain development, axon guidance and cell migration (By similarity). Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SEMA4C

Research Areas

Neuroscience; Cell biology; Developmental biology