SEMA3A Polyclonal Antibody

Ab type

Primary antibody

Background

SEMA3A is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. Semaphorin-3A can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human SEMA3A. AA range:688-737

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

88889

synonyms

SEMA3A; SEMAD; Semaphorin-3A; Semaphorin III; Sema III