SCNN1B Antibody

Size

100ug

Clone Number

Aliases

Amiloride sensitive sodium channel subunit beta antibody; Amiloride-sensitive sodium channel subunit beta antibody; Beta NaCH antibody; Beta-ENaC antibody; Beta-NaCH antibody; ENaC beta antibody; ENaCB antibody; Epithelial Na(+) channel subunit beta antibody; Epithelial Na+ channel beta subunit antibody; Epithelial Na+ channel subunit beta antibody; Epithelial sodium channel beta 2 subunit antibody; Epithelial sodium channel beta 3 subunit antibody; Nonvoltage gated sodium channel 1 beta subunit antibody; Nonvoltage gated sodium channel 1 subunit beta antibody; Nonvoltage-gated sodium channel 1 subunit beta antibody; SCNEB antibody; SCNN 1B antibody; SCNN1B antibody; SCNNB_HUMAN antibody; Sodium channel nonvoltage gated 1 beta (Liddle syndrome) antibody; Sodium channel nonvoltage gated 1 beta antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P51168

Immunogen

Recombinant Human Amiloride-sensitive sodium channel subunit beta protein (554-640AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200

Background

Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SCNN1B

Research Areas

Neuroscience; Cancer; Metabolism; Signal transduction