SCN9A Antibody

Size

100ug

Clone Number

Aliases

ETHA antibody; GEFSP7 antibody; hNE Na antibody; hNE-Na antibody; hNENa antibody; NE NA antibody; NENA antibody; Neuroendocrine sodium channel antibody; Peripheral sodium channel 1 antibody; PN1 antibody; Scn9a antibody; SCN9A_HUMAN antibody; Sodium channel protein type 9 subunit alpha antibody; Sodium channel protein type IX subunit alpha antibody; Sodium channel voltage gated type IX alpha antibody; Sodium channel voltage gated type IX alpha polypeptide antibody; Sodium channel voltage gated type IX alpha subunit antibody; Voltage gated sodium channel alpha subunit Nav1.7 antibody; Voltage gated sodium channel subunit alpha Nav1 antibody; Voltage-gated sodium channel subunit alpha Nav1.7 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q15858

Immunogen

Recombinant Human Sodium channel protein type 9 subunit alpha protein (1849-1988AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200

Background

Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient (PubMed:7720699, PubMed:17167479, PubMed:25240195, PubMed:26680203, PubMed:15385606, PubMed:16988069, PubMed:17145499, PubMed:19369487, PubMed:24311784). It is a tetrodotoxin-sensitive Na(+) channel isoform (PubMed:7720699). Plays a role in pain mechanisms, especially in the development of inflammatory pain (PubMed:17167479, PubMed:17145499, PubMed:19369487, PubMed:24311784).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SCN9A

Research Areas

Neuroscience; Cancer; Metabolism; Signal transduction