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ABCbiolab

SKU:ABCCS46634

SCN8A Antibody

SCN8A Antibody

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Size

100ul

Clone Number

Aliases

CerIII antibody; CIAT antibody; EIEE13 antibody; hNa6/Scn8a voltage gated sodium channel antibody; MED antibody; Motor endplate disease antibody; NaCh 6 antibody; NaCh6 antibody; Nav 1.6 antibody; Nbna1 antibody; peripheral nerve protein type 4 antibody; PN 4 antibody; PN4 antibody; SCN8A antibody; SCN8A_HUMAN antibody; Sodium channel protein type 8 alpha subunit antibody; Sodium channel protein type 8 subunit alpha antibody; Sodium channel protein type VIII alpha subunit antibody; Sodium channel protein type VIII subunit alpha antibody; Sodium channel voltage gated type VIII alpha antibody; Sodium channel voltage gated type VIII alpha polypeptide antibody; Sodium channel voltage gated type VIII alpha subunit antibody; Voltage gated sodium channel subunit alpha Nav1.6 antibody; Voltage-gated sodium channel subunit alpha Nav1.6 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9UQD0

Immunogen

Recombinant Human Sodium channel protein type 8 subunit alpha protein (1350-1440AA)

Raised in

Rabbit

Species Reactivity

Human, Rat

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. In macrophages and melanoma cells, isoform 5 may participate in the control of podosome and invadopodia formation.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SCN8A

Research Areas

Neuroscience

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