Scn4b Polyclonal Antibody

Ab type

Primary antibody

Background

Sodium channel subunit beta-4 encoded by SCN4B is one of several sodium channel beta subunits. These subunits interact with voltage-gated alpha subunits to change sodium channel kinetics. The encoded transmembrane protein forms interchain disulfide bonds with SCN2A. Defects in this gene are a cause of long QT syndrome type 10 (LQT10). Three protein-coding and one non-coding transcript variant have been found for this gene.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human SCN4B. AA range:61-110

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

24969

synonyms

SCN4B; Sodium channel subunit beta-4