SCN11A Antibody

Size

100ug

Clone Number

Aliases

hNaN antibody; NaN antibody; NAV1.9 antibody; Peripheral nerve sodium channel 5 antibody; PN 5 antibody; PN5 antibody; SCN 11A antibody; SCN 12A antibody; Scn11a antibody; SCN12A antibody; SCNBA_HUMAN antibody; Sensory neuron sodium channel 2 antibody; SNS 2 antibody; SNS2 antibody; Sodium channel protein type 11 subunit alpha antibody; Sodium channel protein type XI subunit alpha antibody; Sodium channel voltage gated type XI alpha antibody; Sodium channel voltage gated type XI alpha polypeptide antibody; Sodium channel voltage gated type XI alpha subunit antibody; Sodium channel voltage gated type XII alpha polypeptide antibody; Voltage gated sodium channel Nav1.9 antibody; Voltage gated sodium channel subunit alpha Nav1.9 antibody; Voltage-gated sodium channel subunit alpha Nav1.9 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9UI33

Immunogen

Recombinant Human Sodium channel protein type 11 subunit alpha protein (403-551AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:500-1:1000, IF:1:50-1:200

Background

This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform. Also involved, with the contribution of the receptor tyrosine kinase NTRK2, in rapid BDNF-evoked neuronal depolarization.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SCN11A

Research Areas

Neuroscience