SCIN Antibody

Size

100ug

Clone Number

Aliases

Adseverin antibody; ADSV_HUMAN antibody; KIAA1905 antibody; Scin antibody; Scinderin antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9Y6U3

Immunogen

Recombinant Human Adseverin protein (556-703AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IF; Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:500

Background

Ca(2+)-dependent actin filament-severing protein that is presumed to have a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Regulates chondrocyte proliferation and differentiation. MAP kinases p38 and ERK1/2 mediate the adseverin-induced accelerated differentiation of non-hypertrophic chondrocytes (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SCIN

Research Areas

Signal transduction