SCG5 Antibody

Size

100ul

Clone Number

Aliases

SCG5 antibody; SGNE1Neuroendocrine protein 7B2 antibody; Pituitary polypeptide antibody; Secretogranin V antibody; Secretogranin-5 antibody; Secretory granule endocrine protein I) [Cleaved into: N-terminal peptide; C-terminal peptide] antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P05408

Immunogen

Recombinant Human Neuroendocrine protein 7B2 protein (27-212AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SCG5

Research Areas

Others