SCD Antibody

Size

100ug

Clone Number

Aliases

ACOD_HUMAN antibody; Acyl-CoA desaturase antibody; Delta(9)-desaturase antibody; Delta-9 desaturase antibody; Delta-9-Desaturase antibody; FADS5 antibody; Fatty acid desaturase antibody; PRO0998 antibody; SCD 1 antibody; SCD antibody; SCD1 antibody; Stearoyl-CoA desaturase antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O00767

Immunogen

Recombinant Human Acyl-CoA desaturase protein (10-70AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates (PubMed:15907797, PubMed:18765284). Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (PubMed:15907797, PubMed:18765284). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids (PubMed:15610069). Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation (By similarity). Plays an important role in body energy homeostasis (By similarity). Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SCD

Research Areas

Cancer; Cardiovascular; Metabolism; Signal transduction