SCARA5 Antibody

Size

100ug

Clone Number

Aliases

FLJ23907 antibody; MGC45780 antibody; NET33 antibody; SCAR5_HUMAN antibody; SCARA 5 antibody; scara5 antibody; Scavenger receptor class A member 5 antibody; Scavenger receptor class A; member 5 (putative) antibody; Scavenger receptor class A; member 5 antibody; Scavenger receptor hlg antibody; Tesr antibody; Testis expressed scavenger receptor antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q6ZMJ2

Immunogen

Recombinant Human Scavenger receptor class A member 5 protein (303-428AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200

Background

Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SCARA5

Research Areas

Cancer; Metabolism; Signal transduction