SBDS Antibody

Size

100ug

Clone Number

Aliases

4733401P19Rik antibody; AI836084 antibody; CGI 97 antibody; CGI-97 antibody; FLJ10917 antibody; MGC105922 antibody; Protein 22A3 antibody; Ribosome maturation protein SBDS antibody; sbds antibody; SBDS_HUMAN antibody; SDS antibody; Shwachman Bodian Diamond syndrome protein antibody; Shwachman Bodian Diamond syndrome protein homolog antibody; Shwachman Bodian-Diamond syndrome antibody; Shwachman-Bodian-Diamond syndrome protein antibody; SWDS antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9Y3A5

Immunogen

Recombinant Human Ribosome maturation protein SBDS protein (37-153AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200

Background

Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SBDS

Research Areas

Epigenetics and Nuclear Signaling