Sar1B Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by SAR1B (secretion associated Ras related GTPase 1B) is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in SAR1B are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human SAR1B. AA range:111-160

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

22410

synonyms

SAR1B; SARA2; SARB; GTP-binding protein SAR1b; GTP-binding protein B; GTBPB