SAP18 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex| which includes SIN3| SAP30| HDAC1| HDAC2| RbAp46| RbAp48| and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human SAP18

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

16830

synonyms

SAP18