SAE1 Antibody

Size

100ul

Clone Number

9D8

Aliases

SUMO-activating enzyme subunit 1 (Ubiquitin-like 1-activating enzyme E1A) [Cleaved into: SUMO-activating enzyme subunit 1, N-terminally processed], SAE1, AOS1 SUA1 UBLE1A

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9UBE0

Immunogen

A synthesized peptide derived from human SAE1

Raised in

Species Reactivity

Human

Tested Applications

ELISA, WB, IF; Recommended dilution: WB:1:500-1:5000, IF:1:20-1:200

Background

The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

Clonality

Monoclonal

Isotype

Rabbit IgG

Purification Method

Affinity-chromatography

Conjugate

Non-conjugated

Buffer

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SAE1

Research Areas

Cell biology