SAA1 Monoclonal Antibody

Size

100ug

Clone Number

1F2E1

Aliases

SAA1, Serum amyloid A-1 protein, Amyloid fibril protein AA

Immunogen Species

Human

UniProt ID

P0DJI8

Immunogen

Recombinant Serum amyloid A-1 Protein

Raised in

Mouse

Species Reactivity

Human

Tested Applications

ELISA

Background

Serum amyloid A protein, also named SAA, Amyloid protein A, Amyloid fibril protein AA, SAA1, SAA2 and PIG4, is an acute phase apolipoprotein reactant which is produced mostly by hepatocytes and under regulation of inflammatory cytokines. SAA1 is produced mainly in the liver and circulates in low levels in the blood. SAA1 may play a role in the immune system and facilitate the repair of injured tissues, it also acts as an antibacterial agent, and signals the migration of germ-fighting cells to sites of infection. SAA1 also functions as an apolipoprotein of the HDL complex. The SAA1 cleavage product a designated amyloid protein A is deposited systemically as amyloid in vital organs such as the liver, spleen, and kidneys in chronic inflammatory diseases patients. These deposits are extremely insoluble and resistant to proteolysis; they disrupt tissue structure and compromise performance.

Clonality

Monoclonal

Isotype

IgG2b

Purification Method

>95%,Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 15mmol/L NaN3
Constituents: 0.1mol/L Nacl

Form

liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SAA1

Research Areas

Cardiovascular