S100B Monoclonal Antibody

Size

100ug

Clone Number

1A1B1

Aliases

S100B ,S-100 protein beta chain,S-100 protein subunit beta,S100 calcium-binding protein B

Immunogen Species

Human

UniProt ID

P04271

Immunogen

Recombinant Human S100B protein

Raised in

Mouse

Species Reactivity

Human

Tested Applications

ELISA

Background

Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

Clonality

Monoclonal

Isotype

IgG1

Purification Method

>95%,Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

S100B

Research Areas

Epigenetics and Nuclear Signaling;Cell biology;Stem cells