S100B Antibody

Size

100ul

Clone Number

Aliases

NEF antibody; Protein S100 B antibody; Protein S100-B antibody; S 100 calcium binding protein beta chain antibody; S 100 protein beta chain antibody; S-100 protein beta chain antibody; S-100 protein subunit beta antibody; S100 antibody; S100 calcium binding protein beta (neural) antibody; S100 calcium-binding protein B antibody; S100 protein beta chain antibody; S100B antibody; S100B_HUMAN antibody; S100beta antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P04271

Immunogen

Recombinant Human Protein S100-B protein (1-92AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

S100B

Research Areas

Epigenetics and Nuclear Signaling; Cell biology; Stem cells