S-100A5 Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by S100A5 (S100 calcium binding protein A5) is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has a Ca2+ affinity 20- to 100-fold higher than the other S100 proteins studied under identical conditions. This protein also binds Zn2+ and Cu2+, and Cu2+ strongly which impairs the binding of Ca2+. This protein is expressed in very restricted regions of the adult brain.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human S100A5. AA range:34-83

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

10744

synonyms

S100A5; S100D; Protein S100-A5; Protein S-100D; S100 calcium-binding protein A5