RUNX3 Antibody

Size

100ug

Clone Number

Aliases

Acute myeloid leukemia 2 protein antibody; Acute myeloid leukemia gene 2 antibody; AML 2 antibody; AML2 antibody; CBF alpha 3 antibody; CBF-alpha-3 antibody; CBFA 3 antibody; CBFA3 antibody; Core binding factor alpha 3 subunit antibody; core binding factor antibody; Core binding factor runt domain alpha subunit 3 antibody; Core binding factor subunit alpha 3 antibody; core-binding factor antibody; Core-binding factor subunit alpha-3 antibody; Oncogene AML 2 antibody; Oncogene AML-2 antibody; PEA2 alpha C antibody; PEA2-alpha C antibody; PEBP2 alpha C antibody; PEBP2-alpha C antibody; Pebp2a3 antibody; PEBP2aC antibody; Polyomavirus enhancer binding protein 2 alpha C subunit antibody; Polyomavirus enhancer-binding protein 2 alpha C subunit antibody; runt domain alpha subunit 3 antibody; runt related transcription factor 3 antibody; Runt-related transcription factor 3 antibody; RUNX 3 antibody; Runx3 antibody; RUNX3_HUMAN antibody; SL3 3 enhancer factor 1 alpha C subunit antibody; SL3-3 enhancer factor 1 alpha C subunit antibody; SL3/AKV core binding factor alpha C subunit antibody; SL3/AKV core-binding factor alpha C subunit antibody; Transcription factor AML2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q13761

Immunogen

Recombinant Human Runt-related transcription factor 3 protein (1-415AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse, Rat

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:200-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Background

CBF binds to the core site, 5\\\'-PYGPYGGT-3\\\', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, lck, IL-3 and GM-CSF promoters. In association with ZFHX3, upregulates CDKN1A promoter activity following TGF-beta stimulation (PubMed:20599712).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

RUNX3

Research Areas

Epigenetics and Nuclear Signaling