RUNX1T1 Antibody

Size

100ug

Clone Number

Aliases

Acute myelogenous leukemia 1 translocation 1 cyclin D related antibody; Acute myelogenous leukemia 1 translocation 1 protein antibody; AML1 MTG8 antibody; AML1T1 antibody; CBFA2T1 antibody; CDR antibody; Core binding factor runt domain alpha subunit 2 translocated to 1 antibody; Core binding factor runt domain alpha subunit 2 translocated to 1 cyclin D related antibody; Cyclin D related antibody; Cyclin D related protein antibody; Cyclin-D-related protein antibody; Eight twenty one protein antibody; ETO antibody; ETO protein antibody; MGC2796 antibody; MTG 8 antibody; MTG 8b antibody; MTG8 antibody; MTG8 protein antibody; MTG8_HUMAN antibody; MTG8b antibody; Myeloid translocation gene on 8q22 antibody; Protein CBFA2T1 antibody; Protein ETO antibody; Protein MTG 8 antibody; Protein MTG8 antibody; Runt related transcription factor 1 translocated to 1 (cyclin D related) antibody; Runt related transcription factor 1 translocated to 1 antibody; Runt related transcription factor 1 translocated to 1 cyclin D related antibody; RUNX1 translocation partner 1 antibody; RUNX1T1 antibody; Zinc finger MYND domain containing protein 2 antibody; Zinc finger MYND domain-containing protein 2 antibody; ZMYND 2 antibody; ZMYND2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q06455

Immunogen

Recombinant Human Protein CBFA2T1 protein (416-525AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:2000-1:10000, IHC:1:20-1:200

Background

Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes (PubMed:12559562, PubMed:15203199). Can repress the expression of MMP7 in a ZBTB33-dependent manner (PubMed:23251453). Can repress transactivation mediated by TCF12 (PubMed:16803958). Acts as a negative regulator of adipogenesis (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

RUNX1T1

Research Areas

Epigenetics and Nuclear Signaling; Cancer