RUFY3 Antibody

Size

100ug

Clone Number

Aliases

Protein RUFY3 antibody; rap2 interacting protein x antibody; Rap2 interacting protein x isoform 2 antibody; Rap2-interacting protein x antibody; RIPx antibody; Rpipx antibody; Rufy3 antibody; RUFY3_HUMAN antibody; RUN and FYVE domain containing 3 antibody; Singar antibody; Singar1 antibody; Single axon regulated protein antibody; single axon related 1 antibody; Single axon-regulated protein antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q7L099

Immunogen

Recombinant Human Protein RUFY3 protein (243-352AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IF; Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200

Background

Plays a role in the generation of neuronal polarity formation and axon growth (By similarity). Implicated in the formation of a single axon by developing neurons (By similarity). May inhibit the formation of additional axons by inhibition of PI3K in minor neuronal processes (By similarity). Plays a role in the formation of F-actin-enriched protrusive structures at the cell periphery (PubMed:25766321). Plays a role in cytoskeletal organization by regulating the subcellular localization of FSCN1 and DBN1 at axonal growth cones (By similarity). Promotes gastric cancer cell migration and invasion in a PAK1-dependent manner (PubMed:25766321).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

RUFY3

Research Areas

Signal transduction