RSK3(Phospho Thr353) Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

Catalytic activity:ATP + a protein = ADP + a phosphoprotein.|cofactor:Magnesium.|enzyme regulation:Activated by multiple phosphorylations on threonine and serine residues.|Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.|PTM:Autophosphorylated on Ser-377| as part of the activation process.|Belongs to the protein kinase superfamily.|Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.|Contains 1 AGC-kinase C-terminal domain.|Contains 2 protein kinase domains.|subunit:Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic stimulation.|tissue specificity:Expressed in many tissues. Highest expression in lung and skeletal muscle.|

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human RSK3 (Phospho Thr353)

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

80630

synonyms

RSK3 ;Phospho Thr353; Ribosomal protein S6 kinase alpha-2; S6K-alpha-2; EC 2.7.11.1; 90 kDa ribosomal protein S6 kinase 2; p90-RSK 2; p90RSK2; MAP kinase-activated protein kinase 1c; MAPK-activated protein kinase 1c; MAPKAP kinase 1c; MAPKAPK-1c; Ribosomal S6 kinase 3; RSK-3; pp90RSK3