RSH4A Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a protein that appears to be a component the radial spoke head| as determined by homology to similar proteins in the biflagellate alga Chlamydomonas reinhardtii and other ciliates. Radial spokes| which are regularly spaced along cilia| sperm| and flagella axonemes| consist of a thin 'stalk' and a bulbous 'head' that form a signal transduction scaffold between the central pair of microtubules and dynein. Mutations in this gene cause primary ciliary dyskinesia 1| a disease arising from dysmotility of motile cilia and sperm. Alternative splicing results in multiple transcript variants.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human RSH4A

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

78760

synonyms

RSH4A