RRM1 Monoclonal Antibody

Size

100ug

Clone Number

3D6H5

Aliases

Ribonucleotide Reductase M1,RRM1,RR1

Immunogen Species

Human

UniProt ID

P23921

Immunogen

Recombinant Human RRM1 Protein

Raised in

Mouse

Species Reactivity

Human

Tested Applications

ELISA,IHC;Recommended dilution:IHC:1:50-1:500

Background

This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells.It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor,rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.

Clonality

Monoclonal

Isotype

IgG

Purification Method

>95%,Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

RRM1

Research Areas

Epigenetics and Nuclear Signaling