LCMT2 Antibody / tRNA wybutosine-synthesizing protein 4

Leucine carboxyl methyltransferase 2 is an enzyme that in humans is encoded by the LCMT2 gene. The protein encoded by this intronless gene belongs to the highly variable methyltransferase superfamily. This gene is the inferred homolog of the Saccharomyces cerevisiae carboxymethyltransferase gene PPM2 that is essential for the synthesis of the hypermodified guanosine Wybutosine (yW).