MAFG Antibody / V-maf musculoaponeurotic fibrosarcoma oncogene homolog G

Transcription factor MafG is a bZip Maf transcription factor protein that in humans is encoded by the MAFG gene. Globin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha- and beta-gene clusters. NFE2 DNA-binding activity consists of a heterodimer containing a ubiquitous small Maf protein and the tissue-restricted protein p45 NFE2. Both subunits are members of the activator protein-1-like superfamily of basic leucine zipper (bZIP) proteins.