Parkin Antibody / PRKN / PARK2

E3 ubiquitin-protein ligase parkin,' also called 'Parkinson disease protein 2,' is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. [RefSeq]