ROR2 Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by ROR2 is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in ROR2 can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from ROR2 . at AA range: 450-530

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

104757

synonyms

ROR2; NTRKR2; Tyrosine-protein kinase transmembrane receptor ROR2; Neurotrophic tyrosine kinase; receptor-related 2