ROR2 Antibody

Size

100ug

Clone Number

Aliases

BDB antibody; BDB1 antibody; Brachydactyly type B antibody; EC 2.7.10.1 antibody; MGC163394 antibody; Neurotrophic tyrosine kinase antibody; Neurotrophic tyrosine kinase, receptor related 2 antibody; NTRKR2 antibody; Receptor tyrosine kinase-like orphan receptor 2 antibody; receptor-related 2 antibody; ROR2 antibody; ROR2_HUMAN antibody; Tyrosine protein kinase transmembrane receptor ROR2 antibody; Tyrosine-protein kinase transmembrane receptor Ror2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q01974

Immunogen

Recombinant Human Tyrosine-protein kinase transmembrane receptor ROR2 protein (752-926AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity). Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PubMed:17717073). In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ROR2

Research Areas

Signal transduction; Stem cells