Robo2 Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by ROBO2 (roundabout guidance receptor 2) belongs to the ROBO family, part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human. The encoded protein is a transmembrane receptor for the slit homolog 2 protein and functions in axon guidance and cell migration. Mutations in ROBO2 are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney. Alternative splicing results in multiple transcript variants.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human ROBO2. AA range:237-286

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

151200

synonyms

ROBO2; KIAA1568; Roundabout homolog 2