RNF220 Antibody

Size

100ug

Clone Number

Aliases

RNF220 antibody; C1orf164 antibody; E3 ubiquitin-protein ligase RNF220 antibody; EC 2.3.2.27 antibody; RING finger protein 220 antibody; RING-type E3 ubiquitin transferase RNF220 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q5VTB9

Immunogen

Recombinant Human E3 ubiquitin-protein ligase RNF220 protein (384-472AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:500-1:1000

Background

E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (By similarity). Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling (PubMed:25266658).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

RNF220

Research Areas

Epigenetics and Nuclear Signaling