RNF213 Antibody

Size

100ug

Clone Number

Aliases

ALK lymphoma oligomerization partner on chromosome 17 antibody; C17orf27 antibody; Chromosome 17 open reading frame 27 antibody; E3 ubiquitin-protein ligase RNF213 antibody; FLJ13051 antibody; KIAA1554 antibody; MGC46622 antibody; MGC9929 antibody; MYMY2 antibody; Mysterin antibody; MYSTR antibody; NET57 antibody; RING finger protein 213 antibody; RN213_HUMAN antibody; RNF 213 antibody; RNF213 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q63HN8

Immunogen

Recombinant Human E3 ubiquitin-protein ligase RNF213 protein (202-350AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:500-1:1000, IF:1:200-1:500

Background

E3 ubiquitin-protein ligase involved in angiogenesis (PubMed:21799892, PubMed:26278786, PubMed:26766444, PubMed:26126547). Involved in the non-canonical Wnt signaling pathway in vascular development: acts by mediating ubiquitination and degradation of FLNA and NFATC2 downstream of RSPO3, leading to inhibit the non-canonical Wnt signaling pathway and promoting vessel regression (PubMed:26766444). Also has ATPase activity (PubMed:24658080, PubMed:26126547).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

RNF213

Research Areas