RNASEH2C Antibody

Size

100ug

Clone Number

Aliases

RNASEH2C antibody; AYP1 antibody; Ribonuclease H2 subunit C antibody; RNase H2 subunit C antibody; Aicardi-Goutieres syndrome 3 protein antibody; AGS3 antibody; RNase H1 small subunit antibody; Ribonuclease HI subunit C antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q8TDP1

Immunogen

Recombinant Human Ribonuclease H2 subunit C protein (1-164AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Background

Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

RNASEH2C

Research Areas

Epigenetics and Nuclear Signaling